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A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the ß Secretase Implicated in Alzheimer's Disease.
Mycroft-West, Courtney J; Cooper, Lynsay C; Devlin, Anthony J; Procter, Patricia; Guimond, Scott E; Guerrini, Marco; Fernig, David G; Lima, Marcelo A; Yates, Edwin A; Skidmore, Mark A.
Afiliação
  • Mycroft-West CJ; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Huxley Building, Keele, Staffordshire ST5 5BG, UK. c.j.mycroft-west@keele.ac.uk.
  • Cooper LC; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Huxley Building, Keele, Staffordshire ST5 5BG, UK. l.c.cooper@keele.ac.uk.
  • Devlin AJ; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Huxley Building, Keele, Staffordshire ST5 5BG, UK. a.devlin1@keele.ac.uk.
  • Procter P; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Via G. Colombo 81, 20133 Milan, Italy. a.devlin1@keele.ac.uk.
  • Guimond SE; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Huxley Building, Keele, Staffordshire ST5 5BG, UK. p.procter@keele.ac.uk.
  • Guerrini M; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Huxley Building, Keele, Staffordshire ST5 5BG, UK. s.e.guimond@keele.ac.uk.
  • Fernig DG; Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire ST5 5BG, UK. s.e.guimond@keele.ac.uk.
  • Lima MA; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Via G. Colombo 81, 20133 Milan, Italy. guerrini@ronzoni.it.
  • Yates EA; School of Biological Sciences, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK. dgfernig@liverpool.ac.uk.
  • Skidmore MA; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Huxley Building, Keele, Staffordshire ST5 5BG, UK. mlimagb@gmail.com.
Mar Drugs ; 17(5)2019 May 16.
Article em En | MEDLINE | ID: mdl-31100859
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aspártico Endopeptidases / Braquiúros / Ativação Enzimática / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer / Glicosaminoglicanos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aspártico Endopeptidases / Braquiúros / Ativação Enzimática / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer / Glicosaminoglicanos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article