Occupational exposure to organic particles and combustion products during pregnancy and birth outcome in a nationwide cohort study in Sweden.
Occup Environ Med
; 76(8): 537-544, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31123077
ABSTRACT
OBJECTIVE:
To study if children of women exposed to organic particles and combustion products at work during pregnancy, have an increased risk of low birth weight, preterm birth or small for gestational age.METHODS:
A nationwide cohort of all occupationally active mothers and their children from single births during 1994 to the end of 2012 (1 182 138 observations) was formed. Information on birth outcome was obtained from the medical birth register. Information on absence from work, education, occupation, age, nationality and smoking habits was obtained from national registers. A job exposure matrix (FINJEM) was used to assess the exposure.RESULTS:
Pregnant women with low absence from work and high (>50th percentile) exposure to organic particles had an increased risk of giving birth to children with low birth weight (OR=1.19; 95% CI 1.07 to 1.32), small for gestational age (OR=1.22; 95% CI 1.07 to 1.38) or preterm birth (OR=1.17; 95% CI 1.08 to 1.27). Subgroup analyses showed an increased risk of small for gestational age in association with exposure to oil mist. Exposure to oil mist and cooking fumes was associated with low birth weight. Paper and other organic dust was associated with preterm birth. Exposure to combustion products showed an increased risk of small for gestational age (OR=1.40; 95% CI 1.15 to 1.71).CONCLUSIONS:
The results indicate that occupational exposure to organic particles or combustion products during pregnancy is associated with restriction of fetal growth and preterm birth. More studies are needed to confirm a casual association.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hidrocarbonetos Policíclicos Aromáticos
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Recém-Nascido de Baixo Peso
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Recém-Nascido Pequeno para a Idade Gestacional
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Exposição Ocupacional
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Exposição Materna
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Nascimento Prematuro
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Material Particulado
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Newborn
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Pregnancy
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article