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Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.
van de Kooij, Bert; Creixell, Pau; van Vlimmeren, Anne; Joughin, Brian A; Miller, Chad J; Haider, Nasir; Simpson, Craig D; Linding, Rune; Stambolic, Vuk; Turk, Benjamin E; Yaffe, Michael B.
Afiliação
  • van de Kooij B; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • Creixell P; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, United States.
  • van Vlimmeren A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, United States.
  • Joughin BA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, United States.
  • Miller CJ; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • Haider N; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, United States.
  • Simpson CD; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, United States.
  • Linding R; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, United States.
  • Stambolic V; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • Turk BE; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, United States.
  • Yaffe MB; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, United States.
Elife ; 82019 05 24.
Article em En | MEDLINE | ID: mdl-31124786
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Especificidade por Substrato / Transdução de Sinais / Quinases Relacionadas a NIMA Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Especificidade por Substrato / Transdução de Sinais / Quinases Relacionadas a NIMA Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article