Human translingual neurostimulation alters resting brain activity in high-density EEG.
J Neuroeng Rehabil
; 16(1): 60, 2019 05 27.
Article
em En
| MEDLINE
| ID: mdl-31133021
ABSTRACT
BACKGROUND:
Despite growing evidence of a critical link between neuromodulation technologies and neuroplastic recovery, the underlying mechanisms of these technologies remain elusive.OBJECTIVE:
To investigate physiological evidence of central nervous system (CNS) changes in humans during translingual neurostimulation (TLNS).METHODS:
We used high-density electroencephalography (EEG) to measure changes in resting brain activity before, during, and after high frequency (HF) and low frequency (LF) TLNS.RESULTS:
Wavelet power analysis around Cz and microstate analysis revealed significant changes after 20 min of stimulation compared to baseline. A secondary effect of exposure order was also identified, indicating a differential neuromodulatory influence of HF TLNS relative to LF TLNS on alpha and theta signal power.CONCLUSIONS:
These results further our understanding of the effects of TLNS on underlying resting brain activity, which in the long-term may contribute to the critical link between clinical effect and changes in brain activity.Palavras-chave
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Estimulação Elétrica
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article