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Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.
Strayer, Amy L; Dennys-Rivers, Cassandra N; Ricart, Karina C; Bae, Narae; Beckman, Joseph S; Franco, Maria Clara; Estevez, Alvaro G.
Afiliação
  • Strayer AL; 1 Department of Neuroscience Weill Cornell Medical College, New York, NY10021, USA.
  • Dennys-Rivers CN; 2 Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32826, USA.
  • Ricart KC; 3 Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Bae N; 4 Department of Pharmacology, Weill Cornell Medical College, New York, NY10021, USA.
  • Beckman JS; 5 Department of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, OR 97331, USA.
  • Franco MC; 5 Department of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, OR 97331, USA.
  • Estevez AG; 5 Department of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, OR 97331, USA.
Exp Biol Med (Maywood) ; 244(11): 901-914, 2019 08.
Article em En | MEDLINE | ID: mdl-31142143
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzoquinonas / Apoptose / Proteínas de Choque Térmico HSP90 / Lactamas Macrocíclicas / Receptores Purinérgicos P2X7 / Neurônios Motores Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzoquinonas / Apoptose / Proteínas de Choque Térmico HSP90 / Lactamas Macrocíclicas / Receptores Purinérgicos P2X7 / Neurônios Motores Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article