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Cardiovascular and Renal Outcomes of Incretin-based Therapies: A Review of Recent Clinical Trials.
Kyriakos, Georgios; Quiles-Sanchez, Lourdes V; Garmpi, Anna; Farmaki, Paraskevi; Kyre, Konstantina; Gkogkos, Spyridon; Savvanis, Spyridon; Memi, Eleni.
Afiliação
  • Kyriakos G; Seccion de Endocrinologia y Nutrition, Hospital General Universitario Santa Lucia, Cartagena, Spain.
  • Quiles-Sanchez LV; Centro de Salud Jesús Marín, Murcia, Spain.
  • Garmpi A; Department of Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athen, Athens, Greece.
  • Farmaki P; 1st Department of Pediatrics, "Aghia Sophia Children's Hospital" Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Kyre K; Department of Internal Medicine, KAT General Hospital, Athens, Greece.
  • Gkogkos S; Department of Surgery, Health Center of Peristeri, Athens, Greece.
  • Savvanis S; Department of Internal Medicine, General Hospital of Athens "Elpis", Athens, Greece.
  • Memi E; Unit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion University Hospital, Medical School of Athens, Ethnikon and Kapodistrian University of Athens, Athens, Greece.
Curr Cardiol Rev ; 16(4): 253-257, 2020.
Article em En | MEDLINE | ID: mdl-31161994
ABSTRACT

BACKGROUND:

To report the cardiovascular and renal effects of incretin-based therapies.

METHODS:

The studies of clinical trials on incretin-based therapy published in medical journals from the years 2010 to 2017 were comprehensively searched using MEDLINE and EMBASE with no language restriction. The studies were reviewed and the cardiovascular and renal risks reported were recorded.

RESULTS:

Incretin-based therapeutics represent novel and promising anti-diabetes drugs, the direct cardiovascular actions which may translate into demonstrable clinical benefits on cardiovascular outcomes. Furthermore, incretin-based therapies do not adversely affect renal function.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Cardiovascular / Diabetes Mellitus Tipo 2 / Incretinas Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Cardiovascular / Diabetes Mellitus Tipo 2 / Incretinas Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article