Caspase-11-Mediated Cell Death Contributes to the Pathogenesis of Imiquimod-Induced Psoriasis.

Kenealy, Sinéad; Manils, Joan; Raverdeau, Mathilde; Munoz-Wolf, Natalia; Barber, Gillian; Liddicoat, Alex; Lavelle, Ed C; Creagh, Emma M

Kenealy, Sinéad; Manils, Joan; Raverdeau, Mathilde; Munoz-Wolf, Natalia; Barber, Gillian; Liddicoat, Alex; Lavelle, Ed C; Creagh, Emma M.

Afiliação

Kenealy S; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Manils J; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Raverdeau M; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Munoz-Wolf N; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Barber G; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Liddicoat A; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Lavelle EC; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Creagh EM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. Electronic address: ecreagh@tcd.ie.

J Invest Dermatol ; 139(11): 2389-2393.e3, 2019 11.

Article em En | MEDLINE | ID: mdl-31173764

Assuntos

Caspases Iniciadoras/metabolismo; Inflamação/metabolismo; Psoríase/metabolismo; Pele/metabolismo; Animais; Caspases Iniciadoras/genética; Morte Celular; Proliferação de Células; Modelos Animais de Doenças; Humanos; Imiquimode; Inflamação/patologia; Interleucina-1beta/metabolismo; Camundongos; Camundongos Knockout; Neovascularização Patológica; Psoríase/induzido quimicamente; Psoríase/patologia; Ribonuclease Pancreático/genética; Ribonuclease Pancreático/metabolismo; Pele/patologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Pele / Caspases Iniciadoras / Inflamação Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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