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Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes.
Sorini, Chiara; Cosorich, Ilaria; Lo Conte, Marta; De Giorgi, Lorena; Facciotti, Federica; Lucianò, Roberta; Rocchi, Martina; Ferrarese, Roberto; Sanvito, Francesca; Canducci, Filippo; Falcone, Marika.
Afiliação
  • Sorini C; Experimental Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Cosorich I; Immunology and Allergy Unit, Department of Medicine, Karolinska Institute, SE-171 77 Stockholm, Sweden.
  • Lo Conte M; Experimental Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • De Giorgi L; Experimental Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Facciotti F; Experimental Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Lucianò R; Department of Experimental Oncology, European Institute of Oncology IRCSS, 20139 Milan, Italy.
  • Rocchi M; Pathological Anatomy Unit, IRCSS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Ferrarese R; Pathological Anatomy Unit, IRCSS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Sanvito F; Experimental Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Canducci F; Pathological Anatomy Unit, IRCSS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Falcone M; Department of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.
Proc Natl Acad Sci U S A ; 116(30): 15140-15149, 2019 07 23.
Article em En | MEDLINE | ID: mdl-31182588
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Ilhotas Pancreáticas / Colite / Diabetes Mellitus Tipo 1 / Microbioma Gastrointestinal / Mucosa Intestinal Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Ilhotas Pancreáticas / Colite / Diabetes Mellitus Tipo 1 / Microbioma Gastrointestinal / Mucosa Intestinal Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article