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Kainic acid Induces production and aggregation of amyloid ß-protein and memory deficits by activating inflammasomes in NLRP3- and NF-κB-stimulated pathways.
Ruan, Yang; Qiu, Xiang; Lv, Yu-Dan; Dong, Dong; Wu, Xiu-Juan; Zhu, Jie; Zheng, Xiang-Yu.
Afiliação
  • Ruan Y; Key Laboratory of Pathobiology, Ministry of Education, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
  • Qiu X; Department of Radiology, The First Hospital of Jilin University, Changchun 130021, China.
  • Lv YD; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun 130021, China.
  • Dong D; Department of Radiology, The First Hospital of Jilin University, Changchun 130021, China.
  • Wu XJ; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun 130021, China.
  • Zhu J; Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun 130021, China.
  • Zheng XY; , Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm 141 86, Sweden.
Aging (Albany NY) ; 11(11): 3795-3810, 2019 06 10.
Article em En | MEDLINE | ID: mdl-31182681
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / NF-kappa B / Inflamassomos / Agregados Proteicos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Ácido Caínico / Transtornos da Memória Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / NF-kappa B / Inflamassomos / Agregados Proteicos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Ácido Caínico / Transtornos da Memória Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article