Drug metabolizing enzymes-associated chemo resistance and strategies to overcome it.

Verma, Himanshu; Singh Bahia, Malkeet; Choudhary, Shalki; Kumar Singh, Pankaj; Silakari, Om

Verma, Himanshu; Singh Bahia, Malkeet; Choudhary, Shalki; Kumar Singh, Pankaj; Silakari, Om.

Afiliação

Verma H; MolecularModelling Lab (MML), Department of Pharmaceutical Sciences and Drug Research, Punjabi University , Patiala , India.
Singh Bahia M; Department of Chemistry, Bar-IIan University , Ramat Gan , Israel.
Choudhary S; MolecularModelling Lab (MML), Department of Pharmaceutical Sciences and Drug Research, Punjabi University , Patiala , India.
Kumar Singh P; MolecularModelling Lab (MML), Department of Pharmaceutical Sciences and Drug Research, Punjabi University , Patiala , India.
Silakari O; MolecularModelling Lab (MML), Department of Pharmaceutical Sciences and Drug Research, Punjabi University , Patiala , India.

Drug Metab Rev ; 51(2): 196-223, 2019 05.

Article em En | MEDLINE | ID: mdl-31203662

Assuntos

Enzimas/metabolismo; Preparações Farmacêuticas/metabolismo; Animais; Resistência a Medicamentos; Humanos; Inativação Metabólica; Farmacologia

Palavras-chave

ALDH; CYP450; Cancer; DMEs; DPD; GST; NQO1; UGT; drug resistance

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Enzimas Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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