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Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar, Faisa; Findlay, Jane E; Carfray, Gemma; Allcock, Robert W; Jiang, Zhong; Moore, Caitlin; Muir, Amy L; Lannoy, Morgane; Fertig, Bracy A; Mai, Deborah; Day, Jonathan P; Bolger, Graeme; Baillie, George S; Schwiebert, Erik; Klussmann, Enno; Pyne, Nigel J; Ong, Albert C M; Bowers, Keith; Adam, Julia M; Adams, David R; Houslay, Miles D; Henderson, David J P.
Afiliação
  • Omar F; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Findlay JE; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Carfray G; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Allcock RW; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Jiang Z; Institute of Chemical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, United Kingdom.
  • Moore C; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Muir AL; Institute of Chemical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, United Kingdom.
  • Lannoy M; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Fertig BA; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Mai D; Academic Nephrology Unit, Department of Infection Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield S10 2RX, United Kingdom.
  • Day JP; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
  • Bolger G; DiscoveryBioMed, Inc., Birmingham, AL 35242.
  • Baillie GS; Department of Genetics, University of Cambridge, CB2 3EH Cambridge, United Kingdom.
  • Schwiebert E; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-3300.
  • Klussmann E; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
  • Pyne NJ; DiscoveryBioMed, Inc., Birmingham, AL 35242.
  • Ong ACM; Max-Delbrück-Centrum für Molekulare Medizin, 13092 Berlin, Germany.
  • Bowers K; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Vegetative Physiologie, 10117 Berlin, Germany.
  • Adam JM; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G1 1XQ, Scotland, United Kingdom.
  • Adams DR; Academic Nephrology Unit, Department of Infection Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield S10 2RX, United Kingdom.
  • Houslay MD; Mironid, Ltd., Newhouse, North Lanarkshire ML1 5UH, Scotland, United Kingdom.
  • Henderson DJP; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G1 1XQ, Scotland, United Kingdom.
Proc Natl Acad Sci U S A ; 116(27): 13320-13329, 2019 07 02.
Article em En | MEDLINE | ID: mdl-31209056
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nucleotídeo Cíclico Fosfodiesterase do Tipo 4 Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nucleotídeo Cíclico Fosfodiesterase do Tipo 4 Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article