Assessing mindfulness-based cognitive therapy intervention for tinnitus using behavioural measures and structural MRI: a pilot study.
Int J Audiol
; 58(12): 889-901, 2019 12.
Article
em En
| MEDLINE
| ID: mdl-31223049
ABSTRACT
Objective:
We used a minimally-modified version of Mindfulness-Based Cognitive Therapy (MBCT) to treat symptoms of distress associated with tinnitus.Design:
Audiological screening (establishing a baseline) was conducted prior to treatment and at three time-points pre-intervention, post-intervention and follow-up, 8 weeks after completion of training. MRI tests were also conducted at these three time-points.Study sample Twenty-one participants were enrolled in the study, of whom 15 completed training and audiological testing and eight completed the MRI portion of the study.Results:
Scores on tinnitus-related questionnaires showed a significant decline either from pre- to post-intervention or from pre-intervention to follow-up, despite no significant change during baseline. Voxel-based morphometric analysis of the structural MRI scans revealed clusters in bilateral superior frontal gyrus that exhibited significant increases in grey matter volume over the period of intervention and follow-up. Further, grey matter changes in occipital and cingulate regions correlated with declines in tinnitus handicap.Conclusions:
This pilot study supports MBCT as an adequate approach for treating distressing tinnitus and suggests that neuroanatomical changes may reflect reductions in tinnitus-related severity. Although our small sample size precludes drawing strong conclusions, there is potential for assessing neuroanatomical changes due to mindfulness-based interventions in tinnitus.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Zumbido
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Atenção Plena
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article