Establishment of a rapid and sensitive UPLC-MS/MS method for pharmacokinetic determination of nine alkaloids of crude and processed Corydalis turtschaninovii Besser aqueous extracts in rat plasma.

Tao, Yi; Huang, Surun; Yan, Jizhong; Cai, Baochang

Tao, Yi; Huang, Surun; Yan, Jizhong; Cai, Baochang.

Afiliação

Tao Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, PR China; Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, PR China. Electronic address: taoyi1985812@126.com.
Huang S; Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, PR China.
Yan J; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: yanjz@zjut.edu.cn.
Cai B; Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, PR China.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1124: 218-225, 2019 Aug 15.

Article em En | MEDLINE | ID: mdl-31233942

Assuntos

Alcaloides/sangue; Cromatografia Líquida/métodos; Corydalis/química; Extratos Vegetais/sangue; Espectrometria de Massas em Tandem/métodos; Alcaloides/farmacocinética; Animais; Masculino; Extratos Vegetais/farmacocinética; Ratos; Ratos Sprague-Dawley; Sensibilidade e Especificidade

Palavras-chave

Corydalis turtschaninovii Besser; Pharmacokinetics; UPLC-MS/MS; Vinegar-processed

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Cromatografia Líquida / Corydalis / Alcaloides / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies / Evaluation_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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