Recurrent or first preeclampsia in multiparae: A case-control study of singleton pregnancies in Reunion Island.
Eur J Obstet Gynecol Reprod Biol
; 240: 80-86, 2019 Sep.
Article
em En
| MEDLINE
| ID: mdl-31234061
ABSTRACT
Recurrent or first preeclampsia in multiparae a case-control study of singleton pregnancies in Reunion Island Phuong Lien Tran, Pierre-Yves Robillard, Coralie Dumont, Chloé Schweizer, Asma Omarjee, Glorianne Lazaro, Silvia Iacobelli, Malik Boukerrou OBJECTIVE:
To compare multiparous women with a first occurrence of preeclampsia and those with recurrent preeclampsia in singleton pregnancies. STUDYDESIGN:
a 17.5-year (2001-2018) case-control study conducted in the University's maternity of South Reunion (Indian Ocean), comparing 125 patients with recurrent preeclampsia and 742 patients with a first episode of the disease (controls). Statistical analyses were performed with use of the Student t-test for comparison of continuous data and the Chi-square or Fisher exact test for comparison of categorical variables.RESULTS:
There was no difference between the two groups concerning socio-demographic characteristics, post-partum haemorrhage, perinatal mortality rates. Nevertheless, recurrent preeclamptic women had a higher risk to present with prior chronic hypertension (OR 2.05 [1.30-3.23], pâ¯=â¯0.002), and to experience an early onset preeclampsia (< 34 weeks) compared to controls (OR 1.69 [1.15-2.48], pâ¯=â¯0.007). Women with recurrent preeclampsia were more prone to have C-sections (OR 1.63 [1.06-2.51], pâ¯=â¯0.024) mainly because of maternal indications (89.2% vs 76.4%, pâ¯=â¯0.008). Newborns from recurrent preeclampsia were more likely to have very low birthweight < 1500â¯g (OR 1.79 [1.16-2.77], pâ¯=â¯0.001), while there was no significant difference for gestational ages (34.1 vs 34.7 weeks).CONCLUSION:
Recurrent multiparous preeclamptic women presented more severe maternal disease (with a higher rate of early onset preeclampsia). Persistent hypertension in women with a history of preeclampsia is a risk factor for developing recurrent preeclampsia, and these patients should be monitored more closely.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pré-Eclâmpsia
/
Hipertensão
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article