Thymic stromal lymphopoietin epigenetically upregulates Fc receptor Î³ subunit-related receptors on antigen-presenting cells and induces T<sub>H</sub>2/T<sub>H</sub>17 polarization through dectin-2.

Liang, Yunsheng; Yu, Bihui; Chen, Junchen; Wu, Haijin; Xu, Yingping; Yang, Bin; Lu, Qianjin

Thymic stromal lymphopoietin epigenetically upregulates Fc receptor Î³ subunit-related receptors on antigen-presenting cells and induces T_H2/T_H17 polarization through dectin-2.

Liang, Yunsheng; Yu, Bihui; Chen, Junchen; Wu, Haijin; Xu, Yingping; Yang, Bin; Lu, Qianjin.

Afiliação

Liang Y; Department of Dermatology, Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, China. Electronic address: yunshengliang@aliyun.com.
Yu B; Department of Dermatology, Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, China; Hunan Key Laboratory of Medical Epigenomics & Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China.
Chen J; Department of Dermatology, Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, China.
Wu H; Hunan Key Laboratory of Medical Epigenomics & Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China.
Xu Y; Department of Dermatology, Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, China.
Yang B; Department of Dermatology, Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, China. Electronic address: yangbin101@hotmail.com.
Lu Q; Hunan Key Laboratory of Medical Epigenomics & Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China. Electronic address: qianlu5860@csu.edu.cn.

J Allergy Clin Immunol ; 144(4): 1025-1035.e7, 2019 10.

Article em En | MEDLINE | ID: mdl-31251950

Assuntos

Células Apresentadoras de Antígenos/imunologia; Citocinas/imunologia; Dermatite Atópica/imunologia; Lectinas Tipo C/imunologia; Receptores Fc/biossíntese; Citocinas/metabolismo; Metilação de DNA; Dermatite Atópica/metabolismo; Epigênese Genética; Humanos; Receptores Fc/imunologia; Transdução de Sinais/imunologia; Células Th17/imunologia; Células Th2/imunologia; Ativação Transcricional/imunologia; Regulação para Cima

Palavras-chave

Atopic dermatitis; DNA demethylation; FcRÎ³-related receptors; IL-25; IL-33; T(H)2/T(H)17 polarization; allergen uptake; dectin-2; signal transducer and activator of transcription 5; ten-eleven translocation protein 2; thymic stromal lymphopoietin

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Fc / Citocinas / Lectinas Tipo C / Dermatite Atópica / Células Apresentadoras de Antígenos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google