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Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening.
Zhang, Feng-Cai; Sun, Zhong-Ya; Liao, Li-Ping; Zuo, Yu; Zhang, Dan; Wang, Jun; Chen, Yan-Tao; Xiao, Sen-Hao; Jiang, Hao; Lu, Tian; Xu, Pan; Yue, Li-Yan; Du, Dao-Hai; Zhang, Hao; Liu, Chuan-Peng; Luo, Cheng.
Afiliação
  • Zhang FC; School of Pharmacy, Nanchang University, Nanchang, 330006, China.
  • Sun ZY; School of Life and Technology, Harbin Institute of Technology, Harbin, 150001, China.
  • Liao LP; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zuo Y; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhang D; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Wang J; School of Pharmacy, Nanchang University, Nanchang, 330006, China.
  • Chen YT; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Xiao SH; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Jiang H; Department of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China.
  • Lu T; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Xu P; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
  • Yue LY; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Du DH; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Zhang H; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Liu CP; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Luo C; Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Acta Pharmacol Sin ; 41(2): 286-292, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31253937

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Proteína de Ligação a CREB / Ensaios de Triagem em Larga Escala / Antineoplásicos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Proteína de Ligação a CREB / Ensaios de Triagem em Larga Escala / Antineoplásicos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article