Comparative evaluation of the use of dry binders in a physical mixture or as a coprocessed dry binder in matrix tablets with extended drug release.

Muzíková, Jitka; Komersová, Alena; Lochar, Václav; Vildová, Lucie; Vosoustová, Bára; Bartos, Martin

Muzíková, Jitka; Komersová, Alena; Lochar, Václav; Vildová, Lucie; Vosoustová, Bára; Bartos, Martin.

Afiliação

Muzíková J; Department of Pharmaceutical Technology, Charles University, Faculty of Pharmacy in Hradec Králové, Czech Republic.
Komersová A; Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Czech Republic.
Lochar V; Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Czech Republic.
Vildová L; Department of Pharmaceutical Technology, Charles University, Faculty of Pharmacy in Hradec Králové, Czech Republic.
Vosoustová B; Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Czech Republic.
Bartos M; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Czech Republic.

Acta Pharm ; 68(3): 295-311, 2018 Sep 01.

Article em En | MEDLINE | ID: mdl-31259696

Assuntos

Celulose/química; Excipientes/química; Lactose/química; Tecnologia Farmacêutica/métodos; Química Farmacêutica/métodos; Liberação Controlada de Fármacos; Dinâmica não Linear; Álcool de Polivinil/química; Ácido Salicílico/administração & dosagem; Ácido Salicílico/química; Solubilidade; Comprimidos; Resistência à Tração

Palavras-chave

coprocessed dry binder; dissolution testing; energy profile of compression; matrix tablets; polyvinyl alcohol; tensile strength of tablets

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Celulose / Tecnologia Farmacêutica / Excipientes / Lactose Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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