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TNAP limits TGF-ß-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors.
Arnò, Benedetta; Galli, Francesco; Roostalu, Urmas; Aldeiri, Bashar M; Miyake, Tetsuaki; Albertini, Alessandra; Bragg, Laricia; Prehar, Sukhpal; McDermott, John C; Cartwright, Elizabeth J; Cossu, Giulio.
Afiliação
  • Arnò B; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Galli F; Medicines Discovery Catapult, Mereside, Alderley Edge SK104TG, UK.
  • Roostalu U; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Aldeiri BM; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Miyake T; Gubra Hørsholm Kongevej 11B 2970 Hørsholm, Denmark.
  • Albertini A; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Bragg L; King's College Hospital, Denmark Hill, London SE5 9RS, UK.
  • Prehar S; Department of Biology, York University, Toronto, ON, M3J 1P3, Canada.
  • McDermott JC; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Cartwright EJ; TIGET-HSR, Ospedale San Raffele, Via Olgettina 60, 20132 Milan, Italy.
  • Cossu G; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
J Cell Sci ; 132(15)2019 08 08.
Article em En | MEDLINE | ID: mdl-31289197
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Fator de Crescimento Transformador beta / Músculo Esquelético / Fosfatase Alcalina / Proteína Smad2 / Proteína Smad3 / Miocárdio Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Fator de Crescimento Transformador beta / Músculo Esquelético / Fosfatase Alcalina / Proteína Smad2 / Proteína Smad3 / Miocárdio Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article