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Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma.
Mohlin, Sofie; Hansson, Karin; Radke, Katarzyna; Martinez, Sonia; Blanco-Apiricio, Carmen; Garcia-Ruiz, Cristian; Welinder, Charlotte; Esfandyari, Javanshir; O'Neill, Michael; Pastor, Joaquin; von Stedingk, Kristoffer; Bexell, Daniel.
Afiliação
  • Mohlin S; Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Hansson K; Department of Laboratory Medicine, Translational Cancer Research, Lund University Cancer Center, Lund University, Lund, Sweden.
  • Radke K; Department of Laboratory Medicine, Translational Cancer Research, Lund University Cancer Center, Lund University, Lund, Sweden.
  • Martinez S; Experimental Therapeutics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Blanco-Apiricio C; Experimental Therapeutics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Garcia-Ruiz C; Department of Laboratory Medicine, Translational Cancer Research, Lund University Cancer Center, Lund University, Lund, Sweden.
  • Welinder C; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
  • Esfandyari J; Department of Laboratory Medicine, Translational Cancer Research, Lund University Cancer Center, Lund University, Lund, Sweden.
  • O'Neill M; Inflection Biosciences Ltd, Blackrock, Ireland.
  • Pastor J; Experimental Therapeutics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • von Stedingk K; Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Bexell D; Department of Oncogenomics, University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
EMBO Mol Med ; 11(8): e10058, 2019 08.
Article em En | MEDLINE | ID: mdl-31310053
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Pirimidinas / Tiofenos / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Fosfatidilinositol 3-Quinase / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Neuroblastoma Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Pirimidinas / Tiofenos / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Fosfatidilinositol 3-Quinase / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Neuroblastoma Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article