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HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal.
Masenga, Sepiso K; Hamooya, Benson M; Nzala, Selestine; Kwenda, Geoffrey; Heimburger, Douglas C; Mutale, Wilbroad; Koethe, John R; Kirabo, Annet; Munsaka, Sody M.
Afiliação
  • Masenga SK; School of Medicine and Health Sciences, Mulungushi University, Livingstone, Zambia. smasenga@mu.ac.zm.
  • Hamooya BM; Department of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia. smasenga@mu.ac.zm.
  • Nzala S; Vanderbilt Institute for Global Health, Nashville, TN, USA. smasenga@mu.ac.zm.
  • Kwenda G; School of Medicine and Health Sciences, Mulungushi University, Livingstone, Zambia.
  • Heimburger DC; Department of Epidemiology and Biostatistics, School of Public Health, University of Zambia, Lusaka, Zambia.
  • Mutale W; Department of Medical Education Development, University of Zambia, Lusaka, Zambia.
  • Koethe JR; Department of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
  • Kirabo A; Vanderbilt Institute for Global Health, Nashville, TN, USA.
  • Munsaka SM; Department of Health Policy and Management, School of Public Health, University of Zambia, Lusaka, Zambia.
BMC Res Notes ; 12(1): 424, 2019 Jul 16.
Article em En | MEDLINE | ID: mdl-31311574
OBJECTIVE: The objective of this study is to quantify and compare the effect of excess dietary salt on immune cell activation and blood pressure in HIV versus HIV negative individuals. RESULTS: Salt-sensitivity is associated with increased immune cell activation in animal studies. This concept has not been tested in people living with HIV. This study will therefore add more information in elucidating the interaction between HIV infection and/or anti-retroviral therapy (ART), immune-activation/inflammation and hypertension.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Cloreto de Sódio na Dieta / Antirretrovirais / Hipertensão / Sistema Imunitário Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País como assunto: Africa Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Cloreto de Sódio na Dieta / Antirretrovirais / Hipertensão / Sistema Imunitário Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País como assunto: Africa Idioma: En Ano de publicação: 2019 Tipo de documento: Article