Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism.

Chen, Po-Han; Wu, Jianli; Ding, Chien-Kuang Cornelia; Lin, Chao-Chieh; Pan, Samuel; Bossa, Nathan; Xu, Yitong; Yang, Wen-Hsuan; Mathey-Prevot, Bernard; Chi, Jen-Tsan

Chen, Po-Han; Wu, Jianli; Ding, Chien-Kuang Cornelia; Lin, Chao-Chieh; Pan, Samuel; Bossa, Nathan; Xu, Yitong; Yang, Wen-Hsuan; Mathey-Prevot, Bernard; Chi, Jen-Tsan.

Afiliação

Chen PH; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Wu J; Duke Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Ding CC; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Lin CC; Duke Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Pan S; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Bossa N; Duke Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Xu Y; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Yang WH; Duke Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Mathey-Prevot B; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Chi JT; Duke Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.

Cell Death Differ ; 27(3): 1008-1022, 2020 03.

Article em En | MEDLINE | ID: mdl-31320750

Assuntos

Proteínas Mutadas de Ataxia Telangiectasia/metabolismo; Ferroptose; Proteínas Quinases/metabolismo; Proteoma/metabolismo; Proteínas Mutadas de Ataxia Telangiectasia/antagonistas & inibidores; Proteínas de Transporte de Cátions/metabolismo; Linhagem Celular Tumoral; Cistina/metabolismo; Ferroptose/efeitos dos fármacos; Regulação da Expressão Gênica/efeitos dos fármacos; Humanos; Ferro/metabolismo; Modelos Biológicos; Piperazinas/farmacologia; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Transcrição Gênica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Proteoma / Proteínas Mutadas de Ataxia Telangiectasia / Ferroptose Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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