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Upregulation of p53 through induction of MDM2 degradation: Anthraquinone analogs.
Draganov, Alexander B; Yang, Xiaoxiao; Anifowose, Abiodun; De La Cruz, Ladie Kimberly C; Dai, Chaofeng; Ni, Nanting; Chen, Weixuan; De Los Santos, Zeus; Gu, Lubing; Zhou, Muxiang; Wang, Binghe.
Afiliação
  • Draganov AB; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • Yang X; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • Anifowose A; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • De La Cruz LKC; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • Dai C; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • Ni N; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • Chen W; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • De Los Santos Z; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States.
  • Gu L; Department of Pediatrics and Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, GA 30322, United States.
  • Zhou M; Department of Pediatrics and Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, GA 30322, United States.
  • Wang B; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, United States. Electronic address: wang@gsu.edu.
Bioorg Med Chem ; 27(17): 3860-3865, 2019 09 01.
Article em En | MEDLINE | ID: mdl-31324563
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação para Cima / Proteína Supressora de Tumor p53 / Antraquinonas / Proteínas Proto-Oncogênicas c-mdm2 / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação para Cima / Proteína Supressora de Tumor p53 / Antraquinonas / Proteínas Proto-Oncogênicas c-mdm2 / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article