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Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell lines.
Marampon, Francesco; Di Nisio, Valentina; Pietrantoni, Ilaria; Petragnano, Francesco; Fasciani, Irene; Scicchitano, Bianca Maria; Ciccarelli, Carmela; Gravina, Giovanni Luca; Festuccia, Claudio; Del Fattore, Andrea; Tombolini, Mario; De Felice, Francesca; Musio, Daniela; Cecconi, Sandra; Tini, Paolo; Maddalo, Marta; Codenotti, Silvia; Fanzani, Alessandro; Polimeni, Antonella; Maggio, Roberto; Tombolini, Vincenzo.
Afiliação
  • Marampon F; Department of Radiology, Radiotherapy, Oncology and Anatomopathology, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: francesco.marampon@uniroma1.it.
  • Di Nisio V; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
  • Pietrantoni I; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Petragnano F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Fasciani I; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Scicchitano BM; Institute of Histology and Embryology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy.
  • Ciccarelli C; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Gravina GL; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Festuccia C; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Del Fattore A; Bone Physiopathology Group, Multifactorial Disease and Complex Phenotype Research Area, Bambino Gesù Children's Hospital, Rome, Italy.
  • Tombolini M; Department of Sense Organs, Sapienza University of Rome, Rome, Italy.
  • De Felice F; Department of Radiology, Radiotherapy, Oncology and Anatomopathology, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
  • Musio D; Department of Radiology, Radiotherapy, Oncology and Anatomopathology, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
  • Cecconi S; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
  • Tini P; Radiation Oncology Unit, University Hospital of Siena, Siena, Italy; Sbarro Health Research Organization, Temple University, Philadelphia, PA, United States.
  • Maddalo M; Department of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
  • Codenotti S; Department of Molecular and Translational Medicine, Division of Biotechnology, University of Brescia, Brescia, Italy.
  • Fanzani A; Department of Molecular and Translational Medicine, Division of Biotechnology, University of Brescia, Brescia, Italy.
  • Polimeni A; Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy.
  • Maggio R; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Tombolini V; Department of Radiology, Radiotherapy, Oncology and Anatomopathology, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
Cancer Lett ; 461: 90-101, 2019 Oct 01.
Article em En | MEDLINE | ID: mdl-31325529

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radiossensibilizantes / Rabdomiossarcoma / Sulfonamidas / Diferenciação Celular / Inibidores de Histona Desacetilases / Ácidos Hidroxâmicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radiossensibilizantes / Rabdomiossarcoma / Sulfonamidas / Diferenciação Celular / Inibidores de Histona Desacetilases / Ácidos Hidroxâmicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article