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Microbial Experimental Evolution - a proving ground for evolutionary theory and a tool for discovery.
McDonald, Michael J.
Afiliação
  • McDonald MJ; School of Biological Sciences, Monash University, Melbourne, Vic., Australia.
EMBO Rep ; 20(8): e46992, 2019 08.
Article em En | MEDLINE | ID: mdl-31338963
ABSTRACT
Microbial experimental evolution uses controlled laboratory populations to study the mechanisms of evolution. The molecular analysis of evolved populations enables empirical tests that can confirm the predictions of evolutionary theory, but can also lead to surprising discoveries. As with other fields in the life sciences, microbial experimental evolution has become a tool, deployed as part of the suite of techniques available to the molecular biologist. Here, I provide a review of the general findings of microbial experimental evolution, especially those relevant to molecular microbiologists that are new to the field. I also relate these results to design considerations for an evolution experiment and suggest future directions for those working at the intersection of experimental evolution and molecular biology.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Evolução Molecular Direcionada / Escherichia coli / Evolução Biológica / Modelos Genéticos / Biologia Molecular Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Evolução Molecular Direcionada / Escherichia coli / Evolução Biológica / Modelos Genéticos / Biologia Molecular Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article