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ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of ßTrCP.
Bufalieri, Francesca; Infante, Paola; Bernardi, Flavia; Caimano, Miriam; Romania, Paolo; Moretti, Marta; Lospinoso Severini, Ludovica; Talbot, Julie; Melaiu, Ombretta; Tanori, Mirella; Di Magno, Laura; Bellavia, Diana; Capalbo, Carlo; Puget, Stéphanie; De Smaele, Enrico; Canettieri, Gianluca; Guardavaccaro, Daniele; Busino, Luca; Peschiaroli, Angelo; Pazzaglia, Simonetta; Giannini, Giuseppe; Melino, Gerry; Locatelli, Franco; Gulino, Alberto; Ayrault, Olivier; Fruci, Doriana; Di Marcotullio, Lucia.
Afiliação
  • Bufalieri F; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Infante P; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.
  • Bernardi F; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Caimano M; Institut Curie, PSL Research University, CNRS UMR, INSERM, 91405, Orsay, France.
  • Romania P; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
  • Moretti M; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Lospinoso Severini L; Paediatric Haematology/Oncology Department, Ospedale Pediatrico Bambino Gesù, IRCCS, 00146, Rome, Italy.
  • Talbot J; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Melaiu O; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Tanori M; Institut Curie, PSL Research University, CNRS UMR, INSERM, 91405, Orsay, France.
  • Di Magno L; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
  • Bellavia D; Institut Curie, PSL Research University, CNRS UMR, INSERM, 91405, Orsay, France.
  • Capalbo C; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
  • Puget S; Paediatric Haematology/Oncology Department, Ospedale Pediatrico Bambino Gesù, IRCCS, 00146, Rome, Italy.
  • De Smaele E; Department of Biology, University of Pisa, 56126, Pisa, Italy.
  • Canettieri G; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA), S.Maria di Galeria, 00123, Rome, Italy.
  • Guardavaccaro D; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.
  • Busino L; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Peschiaroli A; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Pazzaglia S; Department of Pediatric Neurosurgery, Necker University Hospital, University Paris Descartes, Sorbonne Paris Cité, 75015, Paris, France.
  • Giannini G; Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
  • Melino G; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Locatelli F; Istituto Pasteur-Fondazione Cenci Bolognetti, University La Sapienza, 00161, Rome, Italy.
  • Gulino A; Department of Biotechnology, University of Verona, 37134, Verona, Italy.
  • Ayrault O; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, PA, USA.
  • Fruci D; National Research Council of Italy CNR, Institute of Translational Pharmacology (IFT), 00133, Rome, Italy.
  • Di Marcotullio L; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA), S.Maria di Galeria, 00123, Rome, Italy.
Nat Commun ; 10(1): 3304, 2019 07 24.
Article em En | MEDLINE | ID: mdl-31341163
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos de Histocompatibilidade Menor / Proteínas Contendo Repetições de beta-Transducina / Proteases Específicas de Ubiquitina / Aminopeptidases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos de Histocompatibilidade Menor / Proteínas Contendo Repetições de beta-Transducina / Proteases Específicas de Ubiquitina / Aminopeptidases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article