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Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function.
Chen, Yandan; Yao, Chunxu; Teng, Yincheng; Jiang, Rongzhen; Huang, Xinxin; Liu, Sheng; Wan, Jun; Broxmeyer, Hal E; Guo, Bin.
Afiliação
  • Chen Y; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
  • Yao C; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
  • Teng Y; Obstetric Intensive Care Center, The Institute of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200233, China.
  • Jiang R; Obstetric Intensive Care Center, The Institute of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200233, China.
  • Huang X; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
  • Liu S; Department of Medical and Molecular Genetics, Center for Computational Biology and Bioinformatics (CCBB), Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
  • Wan J; Department of Medical and Molecular Genetics, Center for Computational Biology and Bioinformatics (CCBB), Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
  • Broxmeyer HE; Department of BioHealth Informatics, School of Informatics and Computing, Indiana University Purdue University Indianapolis (IUPUI), Indianapolis, IN, 46202, USA.
  • Guo B; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. hbroxmey@iupui.edu.
Leukemia ; 33(12): 2962-2966, 2019 12.
Article em En | MEDLINE | ID: mdl-31350528

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Células-Tronco Hematopoéticas / Ésteres de Forbol / Sangue Fetal Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Células-Tronco Hematopoéticas / Ésteres de Forbol / Sangue Fetal Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article