Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability.

Vanhaesebroeck, Bart; Bilanges, Benoit; Madsen, Ralitsa R; Dale, Katie L; Lau, Evelyn; Vladimirou, Elina

Vanhaesebroeck, Bart; Bilanges, Benoit; Madsen, Ralitsa R; Dale, Katie L; Lau, Evelyn; Vladimirou, Elina.

Afiliação

Vanhaesebroeck B; UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK. bart.vanh@ucl.ac.uk.
Bilanges B; UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.
Madsen RR; Centre for Cardiovascular Sciences, Queens Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Dale KL; UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.
Lau E; UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.
Vladimirou E; UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK. e.vladimirou@ucl.ac.uk.

Biomolecules ; 9(8)2019 08 01.

Article em En | MEDLINE | ID: mdl-31374965

Assuntos

Instabilidade Cromossômica/genética; Oncogenes/genética; Fosfatidilinositol 3-Quinases/genética; Ativação Transcricional; Animais; Humanos

Palavras-chave

PI 3-kinase; PI3K inhibitor; cancer; centrosome; chromosomal instability; tumour evolution

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncogenes / Ativação Transcricional / Fosfatidilinositol 3-Quinases / Instabilidade Cromossômica Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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