The impact of obesity on pregnancy outcomes among women with psychiatric disorders: Results from a prospective pregnancy registry.
J Psychosom Res
; 123: 109735, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31376871
ABSTRACT
OBJECTIVE:
Obesity is associated with an increased risk of adverse pregnancy outcomes. As individuals with psychiatric disorders are at a higher risk of obesity than the general population, we aimed to examine the effect of obesity on neonatal and maternal outcomes in this population.METHODS:
Pregnant women with psychiatric disorders were enrolled in the Massachusetts General Hospital National Pregnancy Registry for Psychiatric Medications (NCT01246765) and followed prospectively until 6â¯months postpartum. Pre-pregnancy body mass index was used to categorize participants as normal-weight, overweight, and obese to assess comparative risk of adverse outcomes.RESULTS:
Within our sample of 584 participants (Nâ¯=â¯252 normal-weight; Nâ¯=â¯170 overweight; Nâ¯=â¯162 obese), obesity was not significantly associated with higher risk for birth defects (OR 3.19; 95% CI0.79,12.95; pâ¯=â¯0.10; unadjusted due to the rarity of this outcome in the sample). After adjustment, women with obesity were at higher risk for gestational diabetes (pâ¯=â¯0.011; OR3.23; 95% CI1.30,7.98), as were women in the overweight BMI category (pâ¯=â¯0.003; OR3.77; 95% CI1.58,9.00). Among women with obesity, there was a tendency for a higher C-section rate (pâ¯=â¯0.07) compared to women in the normal-weight BMI category. Other outcomes were not significantly different among groups.CONCLUSIONS:
Peripartum complications associated with obesity are common among women with psychiatric illness; thus, it is important to develop antenatal weight management interventions for this population.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Transtornos Psicóticos
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Resultado da Gravidez
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Obesidade
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Middle aged
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Pregnancy
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article