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Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma.
Calsina, Bruna; Castro-Vega, Luis Jaime; Torres-Pérez, Rafael; Inglada-Pérez, Lucía; Currás-Freixes, Maria; Roldán-Romero, Juan María; Mancikova, Veronika; Letón, Rocío; Remacha, Laura; Santos, María; Burnichon, Nelly; Lussey-Lepoutre, Charlotte; Rapizzi, Elena; Graña, Osvaldo; Álvarez-Escolá, Cristina; de Cubas, Aguirre A; Lanillos, Javier; Cordero-Barreal, Alfonso; Martínez-Montes, Ángel M; Bellucci, Alexandre; Amar, Laurence; Fernandes-Rosa, Fabio Luiz; Calatayud, María; Aller, Javier; Lamas, Cristina; Sastre-Marcos, Júlia; Canu, Letizia; Korpershoek, Esther; Timmers, Henri J; Lenders, Jacques Wm; Beuschlein, Felix; Fassnacht-Capeller, Martin; Eisenhofer, Graeme; Mannelli, Massimo; Al-Shahrour, Fátima; Favier, Judith; Rodríguez-Antona, Cristina; Cascón, Alberto; Montero-Conde, Cristina; Gimenez-Roqueplo, Anne-Paule; Robledo, Mercedes.
Afiliação
  • Calsina B; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Castro-Vega LJ; INSERM, UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris, France.
  • Torres-Pérez R; Université Paris Descartes, PRES Sorbonne Paris Cité, Faculté de Médecine, Paris, France.
  • Inglada-Pérez L; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Currás-Freixes M; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Roldán-Romero JM; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.
  • Mancikova V; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Letón R; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Remacha L; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Santos M; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Burnichon N; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Lussey-Lepoutre C; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Rapizzi E; INSERM, UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris, France.
  • Graña O; Université Paris Descartes, PRES Sorbonne Paris Cité, Faculté de Médecine, Paris, France.
  • Álvarez-Escolá C; Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Génétique, Paris, France.
  • de Cubas AA; INSERM, UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris, France.
  • Lanillos J; Sorbonne Université, Pitié-Salpêtrière Hospital, Department of nuclear medicine, Paris, France.
  • Cordero-Barreal A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
  • Martínez-Montes ÁM; Bioinformatics Unit, Structural Biology Program, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Bellucci A; Servicio de Endocrinología y Nutrición, Hospital Universitario La Paz, Madrid, Spain.
  • Amar L; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Fernandes-Rosa FL; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Calatayud M; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Aller J; Hereditary Endocrine Cancer Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Lamas C; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Radiologie, Paris, France.
  • Sastre-Marcos J; INSERM, UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris, France.
  • Canu L; Université Paris Descartes, PRES Sorbonne Paris Cité, Faculté de Médecine, Paris, France.
  • Korpershoek E; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Hypertension Unit, Paris, France.
  • Timmers HJ; INSERM, UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris, France.
  • Lenders JW; Université Paris Descartes, PRES Sorbonne Paris Cité, Faculté de Médecine, Paris, France.
  • Beuschlein F; Department of Endocrinology and Nutrition Service, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Fassnacht-Capeller M; Department of Endocrinology, Puerta de Hierro University Hospital, Madrid, Spain.
  • Eisenhofer G; Department of Endocrinology, Albacete University Hospital Complex, Albacete, Spain.
  • Mannelli M; Department of Endocrinology, Virgen de la Salud Hospital-Toledo Hospital Complex, Toledo, Spain.
  • Al-Shahrour F; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
  • Favier J; Department of Pathology, Erasmus Medical Center Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • Rodríguez-Antona C; Department of Internal Medicine, Radboud University Medical Centre, 6525 HP Nijmegen, The Netherlands.
  • Cascón A; Department of Internal Medicine, Radboud University Medical Centre, 6525 HP Nijmegen, The Netherlands.
  • Montero-Conde C; Department of Medicine III, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Gimenez-Roqueplo AP; Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany.
  • Robledo M; Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland.
Theranostics ; 9(17): 4946-4958, 2019.
Article em En | MEDLINE | ID: mdl-31410193
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paraganglioma / Neoplasias Encefálicas / Biomarcadores Tumorais / MicroRNAs / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paraganglioma / Neoplasias Encefálicas / Biomarcadores Tumorais / MicroRNAs / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article