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Leptin deficiency reverses high metabolic state and weight loss without affecting central pathology in the R6/2 mouse model of Huntington's disease.
Sjögren, Marie; Soylu-Kucharz, Rana; Dandunna, Unali; Stan, Tiberiu Loredan; Cavalera, Michele; Sandelius, Åsa; Zetterberg, Henrik; Björkqvist, Maria.
Afiliação
  • Sjögren M; Wallenberg Neuroscience Center, Brain Disease Biomarker Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden. Electronic address: marie.sjogren@med.lu.se.
  • Soylu-Kucharz R; Wallenberg Neuroscience Center, Brain Disease Biomarker Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
  • Dandunna U; Wallenberg Neuroscience Center, Brain Disease Biomarker Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
  • Stan TL; Wallenberg Neuroscience Center, Brain Disease Biomarker Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
  • Cavalera M; Department of Clinical Sciences, Cardiovascular Research, Translational Studies, Lund University, Malmö, Sweden.
  • Sandelius Å; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.
  • Zetterberg H; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Neurodegenerative Disease, UCL Institute of
  • Björkqvist M; Wallenberg Neuroscience Center, Brain Disease Biomarker Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
Neurobiol Dis ; 132: 104560, 2019 12.
Article em En | MEDLINE | ID: mdl-31419548
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Redução de Peso / Doença de Huntington / Leptina / Modelos Animais de Doenças / Metabolismo Energético Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Redução de Peso / Doença de Huntington / Leptina / Modelos Animais de Doenças / Metabolismo Energético Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article