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Extracellular vesicles in cancer nanomedicine.
Tarasov, Vadim V; Svistunov, Andrey A; Chubarev, Vladimir N; Dostdar, Samira A; Sokolov, Alexander V; Brzecka, Anna; Sukocheva, Olga; Neganova, Margarita E; Klochkov, Sergey G; Somasundaram, Siva G; Kirkland, Cecil E; Aliev, Gjumrakch.
Afiliação
  • Tarasov VV; Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya St., Moscow 119991, Russia.
  • Svistunov AA; Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya St., Moscow 119991, Russia.
  • Chubarev VN; Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya St., Moscow 119991, Russia.
  • Dostdar SA; Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya St., Moscow 119991, Russia.
  • Sokolov AV; Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya St., Moscow 119991, Russia.
  • Brzecka A; Department of Pulmonology and Lung Cancer, Wroclaw Medical University, Wroclaw, Poland.
  • Sukocheva O; College of Nursing and Health Sciences, Flinders University, Bedford Park, South Australia, Australia.
  • Neganova ME; Institute of Physiologically Active Compounds Russian Academy of Sciences, Chernogolovka, 142432, Russia.
  • Klochkov SG; Institute of Physiologically Active Compounds Russian Academy of Sciences, Chernogolovka, 142432, Russia.
  • Somasundaram SG; Department of Biological Sciences, Salem University, Salem, WV, USA.
  • Kirkland CE; Department of Biological Sciences, Salem University, Salem, WV, USA.
  • Aliev G; Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya St., Moscow 119991, Russia; Institute of Physiologically Active Compounds Russian Academy of Sciences, Chernogolovka, 142432, Russia; GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Anto
Semin Cancer Biol ; 69: 212-225, 2021 02.
Article em En | MEDLINE | ID: mdl-31421263
ABSTRACT
To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Nanomedicina / Nanopartículas / Vesículas Extracelulares / Neoplasias / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Nanomedicina / Nanopartículas / Vesículas Extracelulares / Neoplasias / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article