A cytochrome P450 from the mustard leaf beetles hydroxylates geraniol, a key step in iridoid biosynthesis.

Fu, Nanxia; Yang, Zhi-Ling; Pauchet, Yannick; Paetz, Christian; Brandt, Wolfgang; Boland, Wilhelm; Burse, Antje

Fu, Nanxia; Yang, Zhi-Ling; Pauchet, Yannick; Paetz, Christian; Brandt, Wolfgang; Boland, Wilhelm; Burse, Antje.

Afiliação

Fu N; Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knöll Str. 8, 07745, Jena, Germany.
Yang ZL; Research Group Sequestration and Detoxification in Insects, Max Planck Institute for Chemical Ecology, Hans Knöll Str. 8, 07745, Jena, Germany.
Pauchet Y; Department of Entomology, Max Planck Institute for Chemical Ecology, Hans Knöll Str. 8, 07745, Jena, Germany.
Paetz C; Research Group Biosynthesis/NMR, Max Planck Institute for Chemical Ecology, Hans Knöll Str. 8, 07745, Jena, Germany.
Brandt W; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle (Saale), Germany.
Boland W; Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knöll Str. 8, 07745, Jena, Germany. Electronic address: Boland@ice.mpg.de.
Burse A; Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knöll Str. 8, 07745, Jena, Germany; Department of Medical Technology and Biotechnology, Ernst Abbe Hochschule Jena, Carl Zeiss Promenade 2, 07745, Jena, Germany. Electronic address: aburse@ice.mpg.de.

Insect Biochem Mol Biol ; 113: 103212, 2019 10.

Article em En | MEDLINE | ID: mdl-31425853

Assuntos

Monoterpenos Acíclicos/metabolismo; Besouros/genética; Sistema Enzimático do Citocromo P-450/genética; Proteínas de Insetos/genética; Terpenos/metabolismo; Animais; Besouros/enzimologia; Besouros/crescimento & desenvolvimento; Sistema Enzimático do Citocromo P-450/metabolismo; Hidroxilação; Proteínas de Insetos/metabolismo; Iridoides/metabolismo; Larva/enzimologia; Larva/genética

Palavras-chave

Chemical defense; Chrysomelidae; Fat body; Iridoid; P450 monooxygenase; Phaedon cochleariae

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terpenos / Besouros / Proteínas de Insetos / Sistema Enzimático do Citocromo P-450 / Monoterpenos Acíclicos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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