Stronger estrogenic and antiandrogenic effects on zebrafish larvae displayed by 6:2 polyfluoroalkyl phosphate diester than the 8:2 congener at environmentally relevant concentrations.

Chen, Pengyu; Wang, Ruihan; Yang, Jing; Zhong, Wenjue; Liu, Menglin; Yi, Shujun; Zhu, Lingyan

Chen, Pengyu; Wang, Ruihan; Yang, Jing; Zhong, Wenjue; Liu, Menglin; Yi, Shujun; Zhu, Lingyan.

Afiliação

Chen P; Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Key Laboratory of Pollution Processes and Environmental Criteria of Ministry of Education, College of Environmental Science and Engineering of Nankai University, Tianjin 300350, China.
Wang R; College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, PR China.
Yang J; Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Key Laboratory of Pollution Processes and Environmental Criteria of Ministry of Education, College of Environmental Science and Engineering of Nankai University, Tianjin 300350, China.
Zhong W; Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Key Laboratory of Pollution Processes and Environmental Criteria of Ministry of Education, College of Environmental Science and Engineering of Nankai University, Tianjin 300350, China.
Liu M; Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Key Laboratory of Pollution Processes and Environmental Criteria of Ministry of Education, College of Environmental Science and Engineering of Nankai University, Tianjin 300350, China.
Yi S; Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Key Laboratory of Pollution Processes and Environmental Criteria of Ministry of Education, College of Environmental Science and Engineering of Nankai University, Tianjin 300350, China.
Zhu L; Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Key Laboratory of Pollution Processes and Environmental Criteria of Ministry of Education, College of Environmental Science and Engineering of Nankai University, Tianjin 300350, China. Electronic address: zhuly@nankai.edu.cn.

Sci Total Environ ; 695: 133907, 2019 Dec 10.

Article em En | MEDLINE | ID: mdl-31425999

Assuntos

Estrogênios/toxicidade; Organofosfatos/toxicidade; Poluentes Químicos da Água/toxicidade; Animais; Testes de Toxicidade; Peixe-Zebra/fisiologia

Palavras-chave

Androgen receptor; Estrogen receptor; Molecular docking; Molecular dynamic simulations; Polyfluoroalkyl phosphate esters; Zebrafish

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organofosfatos / Poluentes Químicos da Água / Estrogênios Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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