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Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor.
Li, Linhao; Welch, Matthew A; Li, Zhihui; Mackowiak, Bryan; Heyward, Scott; Swaan, Peter W; Wang, Hongbing.
Afiliação
  • Li L; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.).
  • Welch MA; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.).
  • Li Z; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.).
  • Mackowiak B; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.).
  • Heyward S; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.).
  • Swaan PW; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.).
  • Wang H; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., M.A.W., Z.L., B.M., P.W.S., H.W.); and BioIVT, Halethorpe, Maryland (S.H.) hongbing.wang@rx.umaryland.edu.
Mol Pharmacol ; 96(3): 345-354, 2019 09.
Article em En | MEDLINE | ID: mdl-31436536

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenobarbital / Receptores Citoplasmáticos e Nucleares / Receptor de Pregnano X Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenobarbital / Receptores Citoplasmáticos e Nucleares / Receptor de Pregnano X Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article