Pharmacotherapy of psychiatric inpatients with adjustment disorder: current status and changes between 2000 and 2016.
Eur Arch Psychiatry Clin Neurosci
; 270(1): 107-117, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31440829
ABSTRACT
Adjustment disorder is a temporary change in behaviour or emotion as a reaction to a stress factor. Therapy consists of psychotherapy, and pharmacotherapy can be advised. However, data on the real-life pharmacological treatment are sparse. Prescription data for 4.235 psychiatric inpatients diagnosed with adjustment disorder in the time period 2000-2016 were analysed. The data were obtained from the Drug Safety Programme in Psychiatry (AMSP). Data were collected on two reference days per year; prescription patterns and changes over time were analysed. Of all patients, 81.2% received some type of psychotropic drug. Mostly antidepressants (59.8%), antipsychotics (35.5%), and tranquilisers (22.6%) were prescribed. Prescription rates for antidepressants decreased slightly over the years, while rates for antipsychotics increased, especially for atypical antipsychotics. It is important to note that the diagnosis "adjustment disorder" is most likely a working diagnosis that is used for patients in immediate need of psychiatric aid. Overall, pharmacotherapy for inpatients with this diagnosis is mostly symptom-oriented and focuses on depressive moods, agitation and anxiety. Therapy regimes changed over time and show an increased use of atypical antipsychotics with sedative properties. However, for most of the medication, there are neither evidence-based studies nor guidelines, and drugs might be contraindicated in some cases.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prescrições de Medicamentos
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Psicotrópicos
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Padrões de Prática Médica
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Transtornos de Adaptação
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Monitoramento de Medicamentos
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Pacientes Internados
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Transtornos Mentais
Tipo de estudo:
Diagnostic_studies
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Guideline
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Prognostic_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article