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Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-ß fibrils.
Kannaian, Bhuvaneswari; Sharma, Bhargy; Phillips, Margaret; Chowdhury, Anup; Manimekalai, Malathy S S; Adav, Sunil S; Ng, Justin T Y; Kumar, Ambrish; Lim, Sierin; Mu, Yuguang; Sze, Siu K; Grüber, Gerhard; Pervushin, Konstantin.
Afiliação
  • Kannaian B; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Sharma B; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Phillips M; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Chowdhury A; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Manimekalai MSS; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Adav SS; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Ng JTY; Singapore Phenome Centre, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 636921, Singapore.
  • Kumar A; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Lim S; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Mu Y; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
  • Sze SK; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Grüber G; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
  • Pervushin K; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
Sci Rep ; 9(1): 12579, 2019 08 29.
Article em En | MEDLINE | ID: mdl-31467325

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Chaperonas Moleculares / Oxirredutases Intramoleculares / Lipocalinas / Agregados Proteicos / Neuroproteção Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Chaperonas Moleculares / Oxirredutases Intramoleculares / Lipocalinas / Agregados Proteicos / Neuroproteção Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article