Casein nanoparticles in combination with 2-hydroxypropyl-ß-cyclodextrin improves the oral bioavailability of quercetin.

Peñalva, Rebeca; Esparza, Irene; Morales-Gracia, Jorge; González-Navarro, Carlos J; Larrañeta, Eneko; Irache, Juan M

Peñalva, Rebeca; Esparza, Irene; Morales-Gracia, Jorge; González-Navarro, Carlos J; Larrañeta, Eneko; Irache, Juan M.

Afiliação

Peñalva R; Department of Chemistry and Pharmaceutical Technology, NANO-VAC Research Group, University of Navarra, Spain.
Esparza I; Department of Chemistry and Pharmaceutical Technology, NANO-VAC Research Group, University of Navarra, Spain.
Morales-Gracia J; Department of Chemistry and Pharmaceutical Technology, NANO-VAC Research Group, University of Navarra, Spain.
González-Navarro CJ; Department of Chemistry and Pharmaceutical Technology, NANO-VAC Research Group, University of Navarra, Spain.
Larrañeta E; Department of Chemistry and Pharmaceutical Technology, NANO-VAC Research Group, University of Navarra, Spain.
Irache JM; Department of Chemistry and Pharmaceutical Technology, NANO-VAC Research Group, University of Navarra, Spain. Electronic address: jmirache@unav.es.

Int J Pharm ; 570: 118652, 2019 Oct 30.

Article em En | MEDLINE | ID: mdl-31472219

Assuntos

2-Hidroxipropil-beta-Ciclodextrina/química; Caseínas/química; Nanopartículas/química; Quercetina/química; Quercetina/farmacocinética; Administração Oral; Animais; Disponibilidade Biológica; Portadores de Fármacos/química; Flavonoides/química; Masculino; Polietilenoglicóis/química; Ratos; Ratos Wistar

Palavras-chave

Casein; Cyclodextrin; Nanoparticles; Nutraceutical; Oral delivery; Quercetin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quercetina / Caseínas / Nanopartículas / 2-Hidroxipropil-beta-Ciclodextrina Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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