Endocuff Vision is safe to use for dysplasia surveillance in patients with ulcerative colitis: a feasibility study.
Endosc Int Open
; 7(9): E1044-E1048, 2019 Sep.
Article
em En
| MEDLINE
| ID: mdl-31475220
ABSTRACT
Background and study aims Endocuff Vision improves adenoma detection rates in patients without inflammatory bowel disease. This study aimed to investigate the safety and feasibility of Endocuff Vision-assisted high-definition white light endoscopy (HDWLE) with dye-spray chromoendoscopy for detection of dysplasia in patients with ulcerative colitis. Patients and methods Patients with clinically inactive ulcerative colitis due for dysplasia surveillance were recruited. Procedural endpoints included safety, cecal intubation rate (CIR), terminal ileum intubation rate (TIR), withdrawal time, polyp detection rate, dysplasia detection rate (DDR), and sessile serrated lesion detection rate. Results Twenty-five patients (9 female, median age 57 [range 28â-â82] years) were studied. Endocuff Vision-assisted HDWLE was completed in all participants, with a CIR of 100â%, in a median 4 minutes (range 2â-â16), and a TIR of 88% in a median of 6.5 minutes (range 3â-â19). Median withdrawal time was 18 minutes (range 10â-â55), including application of dye-spray, biopsies and polypectomy. The Mayo Endoscopic subscore was 0 in 11, 1 in 9, and 2 in 5 patients. The DDR was 24â% (6 patients had a total of 12 dysplastic lesions) and sessile serrated lesion detection rate was 12â% (3 patients had a total of 4 sessile serrated polyps). No serious adverse events occurred, with one patient developing clinically insignificant minor mucosal bleeding. Conclusion Endocuff Vision-assisted HDWLE is feasible and safe in patients with ulcerative colitis undergoing dysplasia surveillance. Further studies are required to assess superiority of this technique compared with standard high-definition white light endoscopy with chromoendoscopy.
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Screening_studies
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article