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MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.
Bi, Jianling; Areecheewakul, Sudartip; Li, Yujun; Yang, Shujie; Zhang, Yuping; Ebeid, Kareem; Li, Long; Thiel, Kristina W; Zhang, Jun; Dai, Donghai; Salem, Aliasger K; Leslie, Kimberly K; Meng, Xiangbing.
Afiliação
  • Bi J; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Areecheewakul S; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.
  • Li Y; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Yang S; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA.
  • Zhang Y; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Ebeid K; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.
  • Li L; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Thiel KW; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  • Zhang J; Division of Medical Oncology, Department of Internal Medicine, University of Kansas Medical / Cancer Centers, Kansas City, KS 66160.
  • Dai D; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA.
  • Salem AK; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA.
  • Leslie KK; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA.
  • Meng X; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA. Electronic address: xiangbing-meng@uiowa.edu.
Gynecol Oncol ; 155(2): 349-358, 2019 11.
Article em En | MEDLINE | ID: mdl-31477281

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Proteínas de Grupos de Complementação da Anemia de Fanconi / Proteína do Grupo de Complementação D2 da Anemia de Fanconi / Proteínas de Membrana / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Proteínas de Grupos de Complementação da Anemia de Fanconi / Proteína do Grupo de Complementação D2 da Anemia de Fanconi / Proteínas de Membrana / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article