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Structural basis for a highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain.
Koesoema, Afifa Ayu; Sugiyama, Yosuke; Xu, Zichang; Standley, Daron M; Senda, Miki; Senda, Toshiya; Matsuda, Tomoko.
Afiliação
  • Koesoema AA; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho Midori-ku, Yokohama, 226-8501, Japan.
  • Sugiyama Y; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho Midori-ku, Yokohama, 226-8501, Japan.
  • Xu Z; Department of Genome Informatics, Genome Information Research Center, Research Institute of Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Standley DM; Department of Genome Informatics, Genome Information Research Center, Research Institute of Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. standley@biken.osaka-u.ac.jp.
  • Senda M; Structural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), 1-1 Oho Tsukuba, Ibaraki, 305-0801, Japan.
  • Senda T; Structural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), 1-1 Oho Tsukuba, Ibaraki, 305-0801, Japan. toshiya.senda@kek.jp.
  • Matsuda T; Department of Materials Structure Science, School of High Energy Accelerator Science, SOKENDAI (The Graduate University for Advanced Studies), 1-1 Oho, Tsukuba, Ibaraki, 305-0801, Japan. toshiya.senda@kek.jp.
Appl Microbiol Biotechnol ; 103(23-24): 9543-9553, 2019 Dec.
Article em En | MEDLINE | ID: mdl-31482280
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases / Carbono / Oxirredutases do Álcool / Cetonas Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases / Carbono / Oxirredutases do Álcool / Cetonas Idioma: En Ano de publicação: 2019 Tipo de documento: Article