Human umbilical cord blood monocytes, but not adult blood monocytes, rescue brain cells from hypoxic-ischemic injury: Mechanistic and therapeutic implications.

Saha, Arjun; Patel, Sachit; Xu, Li; Scotland, Paula; Schwartzman, Jonathan; Filiano, Anthony J; Kurtzberg, Joanne; Balber, Andrew E

Saha, Arjun; Patel, Sachit; Xu, Li; Scotland, Paula; Schwartzman, Jonathan; Filiano, Anthony J; Kurtzberg, Joanne; Balber, Andrew E.

Afiliação

Saha A; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Patel S; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Xu L; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Scotland P; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Schwartzman J; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Filiano AJ; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Kurtzberg J; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.
Balber AE; Marcus Center for Cellular Cures (MC3), Duke University School of Medicine, Durham, North Carolina, United States of America.

PLoS One ; 14(9): e0218906, 2019.

Article em En | MEDLINE | ID: mdl-31483780

Assuntos

Comunicação Celular; Sangue Fetal/citologia; Hipóxia-Isquemia Encefálica/metabolismo; Hipóxia-Isquemia Encefálica/patologia; Microglia/metabolismo; Monócitos/metabolismo; Neurônios/metabolismo; Animais; Biomarcadores; Sobrevivência Celular; Células Cultivadas; Citocinas/metabolismo; Glucose/metabolismo; Hipóxia-Isquemia Encefálica/terapia; Imunofenotipagem; Leucócitos Mononucleares/metabolismo; Camundongos; Monócitos/citologia; Oxigênio/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Comunicação Celular / Microglia / Hipóxia-Isquemia Encefálica / Sangue Fetal / Neurônios Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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