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Dynorphin-based "release on demand" gene therapy for drug-resistant temporal lobe epilepsy.
Agostinho, Alexandra S; Mietzsch, Mario; Zangrandi, Luca; Kmiec, Iwona; Mutti, Anna; Kraus, Larissa; Fidzinski, Pawel; Schneider, Ulf C; Holtkamp, Martin; Heilbronn, Regine; Schwarzer, Christoph.
Afiliação
  • Agostinho AS; Department of Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.
  • Mietzsch M; Institute of Virology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Zangrandi L; Department of Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.
  • Kmiec I; Department of Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.
  • Mutti A; Department of Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.
  • Kraus L; Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Epilepsy-Center Berlin-Brandenburg, Berlin, Germany.
  • Fidzinski P; Berlin Institute of Health (BIH), Berlin, Germany.
  • Schneider UC; Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Epilepsy-Center Berlin-Brandenburg, Berlin, Germany.
  • Holtkamp M; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Heilbronn R; Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Epilepsy-Center Berlin-Brandenburg, Berlin, Germany.
  • Schwarzer C; Berlin Institute of Health (BIH), Berlin, Germany.
EMBO Mol Med ; 11(10): e9963, 2019 10.
Article em En | MEDLINE | ID: mdl-31486590
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dinorfinas / Terapia Genética / Expressão Gênica / Neurotransmissores / Epilepsia do Lobo Temporal Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dinorfinas / Terapia Genética / Expressão Gênica / Neurotransmissores / Epilepsia do Lobo Temporal Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article