Your browser doesn't support javascript.
loading
Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering.
van der Schoot, Johan M S; Fennemann, Felix L; Valente, Michael; Dolen, Yusuf; Hagemans, Iris M; Becker, Anouk M D; Le Gall, Camille M; van Dalen, Duco; Cevirgel, Alper; van Bruggen, Jaco A C; Engelfriet, Melanie; Caval, Tomislav; Bentlage, Arthur E H; Fransen, Marieke F; Nederend, Maaike; Leusen, Jeanette H W; Heck, Albert J R; Vidarsson, Gestur; Figdor, Carl G; Verdoes, Martijn; Scheeren, Ferenc A.
Afiliação
  • van der Schoot JMS; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Fennemann FL; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Valente M; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Dolen Y; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Hagemans IM; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Becker AMD; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Le Gall CM; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • van Dalen D; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Cevirgel A; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • van Bruggen JAC; Division of Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands.
  • Engelfriet M; Division of Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands.
  • Caval T; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.
  • Bentlage AEH; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, The Netherlands, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Plesmanlaan 125, Amsterdam 1066 CX, Netherlands.
  • Fransen MF; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, Netherlands.
  • Nederend M; Laboratory for Translational Immunology, UMC Utrecht, Utrecht, Netherlands.
  • Leusen JHW; Laboratory for Translational Immunology, UMC Utrecht, Utrecht, Netherlands.
  • Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.
  • Vidarsson G; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, The Netherlands, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Plesmanlaan 125, Amsterdam 1066 CX, Netherlands.
  • Figdor CG; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Verdoes M; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26, 6525 GA Nijmegen, Netherlands.
  • Scheeren FA; Department of Medical Oncology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, Netherlands.
Sci Adv ; 5(8): eaaw1822, 2019 08.
Article em En | MEDLINE | ID: mdl-31489367
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Hibridomas / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Hibridomas / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article