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Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting.
Thomann, Marco; Malik, Sebastian; Kuhne, Felix; Avenal, Cecile; Plath, Friederike; Bonnington, Lea; Reusch, Dietmar; Bulau, Patrick; Cymer, Florian.
Afiliação
  • Thomann M; Pharma Technical Development Analytics Biologics, Roche Diagnostics GmbH, Nonnenwald 2, D-82377, Penzberg, Germany.
  • Malik S; Pharma Technical Development Analytics Biologics, Roche Diagnostics GmbH, Nonnenwald 2, D-82377, Penzberg, Germany.
  • Kuhne F; Pharma Technical Development Analytics Biologics, Roche Diagnostics GmbH, Nonnenwald 2, D-82377, Penzberg, Germany.
  • Avenal C; Institute for Hygiene, University of Muenster, Robert-Koch-Strasse 41, 48149, Muenster, Germany.
  • Plath F; Pharma Technical Development Analytics Biologics, F Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Bonnington L; Pharma Technical Development Analytics Biologics, F Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Reusch D; Pharma Technical Development Analytics Biologics, Roche Diagnostics GmbH, Nonnenwald 2, D-82377, Penzberg, Germany.
  • Bulau P; Pharma Technical Development Analytics Biologics, Roche Diagnostics GmbH, Nonnenwald 2, D-82377, Penzberg, Germany.
  • Cymer F; Pharma Technical Development Analytics Biologics, Roche Diagnostics GmbH, Nonnenwald 2, D-82377, Penzberg, Germany.
Bioanalysis ; 11(15): 1437-1449, 2019 Aug.
Article em En | MEDLINE | ID: mdl-31490109
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Receptores de IgG / Ácido N-Acetilneuramínico / Fucose / Citotoxicidade Celular Dependente de Anticorpos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Receptores de IgG / Ácido N-Acetilneuramínico / Fucose / Citotoxicidade Celular Dependente de Anticorpos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article