Human amnion-derived mesenchymal stem cells enhance the osteogenic differentiation of human adipose-derived stem cells by promoting adiponectin excretion via the APPL1-ERK1/2 signaling pathway.

Wang, Yuli; Du, Yifei; Yuan, Hua; Pan, Yongchu; Wu, Jun; Du, Xin; Hao, Shushu; Yan, Zixin; Li, Xuan; Liu, Keyue; Xu, Fan

Wang, Yuli; Du, Yifei; Yuan, Hua; Pan, Yongchu; Wu, Jun; Du, Xin; Hao, Shushu; Yan, Zixin; Li, Xuan; Liu, Keyue; Xu, Fan.

Afiliação

Wang Y; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Du Y; Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China.
Yuan H; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Pan Y; Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China.
Wu J; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Du X; Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China.
Hao S; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Yan Z; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy Histology and Embryology, Nanjing Medical University, Nanjing, China.
Li X; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Liu K; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Xu F; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.

IUBMB Life ; 72(2): 296-304, 2020 02.

Article em En | MEDLINE | ID: mdl-31509344

Assuntos

Adiponectina/metabolismo; Tecido Adiposo/citologia; Âmnio/citologia; Diferenciação Celular; Células-Tronco Mesenquimais/citologia; Osteoblastos/citologia; Células-Tronco/citologia; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Tecido Adiposo/metabolismo; Âmnio/metabolismo; Células Cultivadas; Humanos; Células-Tronco Mesenquimais/metabolismo; Proteína Quinase 1 Ativada por Mitógeno/metabolismo; Proteína Quinase 3 Ativada por Mitógeno/metabolismo; Osteoblastos/metabolismo; Fosforilação; Transdução de Sinais; Células-Tronco/metabolismo

Palavras-chave

APPL1-ERK1/2 signaling pathway; adiponectin; human adipose-derived stem cells; human amnion-derived mesenchymal stem cell; osteogenic differentiation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoblastos / Células-Tronco / Diferenciação Celular / Tecido Adiposo / Adiponectina / Células-Tronco Mesenquimais / Âmnio Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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