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Sperm-Mediated Genetic Modifications.
Lavitrano, Marialuisa; Farina, Laura; Cerrito, Maria Grazia; Giovannoni, Roberto.
Afiliação
  • Lavitrano M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy. marialuisa.lavitrano@unimib.it.
  • Farina L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Cerrito MG; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Giovannoni R; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Methods Mol Biol ; 2066: 125-132, 2020.
Article em En | MEDLINE | ID: mdl-31512213
The ability to introduce controlled modifications of the genome of animals represents an important tool for biomedical and veterinary research. Among transgenic techniques, we describe here the sperm-mediated gene transfer method that is based on the spontaneous ability of sperm cells to bind and internalize exogenous DNA and to carry it to the oocyte during fertilization, producing genetically modified animals.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espermatozoides / Animais Geneticamente Modificados / Técnicas de Transferência de Genes / Edição de Genes Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espermatozoides / Animais Geneticamente Modificados / Técnicas de Transferência de Genes / Edição de Genes Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article