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Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4).
Brooks, Carl A; Barton, Linda S; Behm, David J; Brnardic, Edward J; Costell, Melissa H; Holt, Dennis A; Jolivette, Larry J; Matthews, Jay M; McAtee, John J; McCleland, Brent W; Patterson, Jaclyn R; Pero, Joseph E; Rivero, Ralph A; Roethke, Theresa J; Sanchez, Robert M; Shenje, Raynold; Terrell, Lamont R; Lawhorn, Brian G.
Afiliação
  • Brooks CA; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Barton LS; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Behm DJ; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Brnardic EJ; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Costell MH; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Holt DA; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Jolivette LJ; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Matthews JM; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • McAtee JJ; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • McCleland BW; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Patterson JR; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Pero JE; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Rivero RA; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Roethke TJ; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Sanchez RM; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Shenje R; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Terrell LR; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
  • Lawhorn BG; Heart Failure Discovery Performance Unit and Flexible Discovery Unit , GlaxoSmithKline , Collegeville , Pennsylvania 19426 , United States.
J Med Chem ; 62(20): 9270-9280, 2019 10 24.
Article em En | MEDLINE | ID: mdl-31532662
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinas / Sulfonamidas / Canais de Cátion TRPV Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinas / Sulfonamidas / Canais de Cátion TRPV Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article