Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover.

Davis, Hannah M; Deosthale, Padmini J; Pacheco-Costa, Rafael; Essex, Alyson L; Atkinson, Emily G; Aref, Mohammad W; Dilley, Julian E; Bellido, Teresita; Ivan, Mircea; Allen, Matthew R; Plotkin, Lilian I

Davis, Hannah M; Deosthale, Padmini J; Pacheco-Costa, Rafael; Essex, Alyson L; Atkinson, Emily G; Aref, Mohammad W; Dilley, Julian E; Bellido, Teresita; Ivan, Mircea; Allen, Matthew R; Plotkin, Lilian I.

Afiliação

Davis HM; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Deosthale PJ; Center for Musculoskeletal Health, Indianapolis, IN, USA.
Pacheco-Costa R; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Essex AL; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Atkinson EG; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Aref MW; Center for Musculoskeletal Health, Indianapolis, IN, USA.
Dilley JE; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Bellido T; Center for Musculoskeletal Health, Indianapolis, IN, USA.
Ivan M; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Allen MR; Center for Musculoskeletal Health, Indianapolis, IN, USA.
Plotkin LI; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.

FEBS J ; 287(5): 941-963, 2020 03.

Article em En | MEDLINE | ID: mdl-31532878

Assuntos

MicroRNAs/metabolismo; Osteócitos/citologia; Osteócitos/metabolismo; Absorciometria de Fóton; Animais; Fenômenos Biomecânicos; Peso Corporal/fisiologia; Densidade Óssea/fisiologia; Sobrevivência Celular/genética; Sobrevivência Celular/fisiologia; Feminino; Masculino; Camundongos; MicroRNAs/genética; Osteoclastos/citologia; Osteoclastos/metabolismo; Reação em Cadeia da Polimerase Via Transcriptase Reversa

Palavras-chave

apoptosis; bone; cytokine; miR21; microRNA; osteocyte; sexual-dimorphism

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteócitos / MicroRNAs Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteócitos / MicroRNAs Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article