Cell-surface markers identify tissue resident multipotential stem/stromal cell subsets in synovial intimal and sub-intimal compartments with distinct chondrogenic properties.

Sivasubramaniyan, K; Koevoet, W J L M; Hakimiyan, A A; Sande, M; Farrell, E; Hoogduijn, M J; Verhaar, J A N; Chubinskaya, S; Bühring, H-J; van Osch, G J V M

Sivasubramaniyan, K; Koevoet, W J L M; Hakimiyan, A A; Sande, M; Farrell, E; Hoogduijn, M J; Verhaar, J A N; Chubinskaya, S; Bühring, H-J; van Osch, G J V M.

Afiliação

Sivasubramaniyan K; Department of Orthopaedics, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Koevoet WJLM; Department of Otorhinolaryngology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Hakimiyan AA; Department of Pediatrics, Rush University Medical Center, Chicago, IL, USA.
Sande M; Department of Orthopaedics, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Farrell E; Department of Oral and Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Hoogduijn MJ; Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Verhaar JAN; Department of Orthopaedics, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Chubinskaya S; Department of Pediatrics, Rush University Medical Center, Chicago, IL, USA.
Bühring HJ; Department of Internal Medicine II, Division of Hematology, University Clinic of Tübingen, Tübingen, Germany.
van Osch GJVM; Department of Orthopaedics, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Otorhinolaryngology, Erasmus MC University Medical Center, Rotterdam, the Netherlands. Electronic address: g.vanosch@erasmusmc.nl.

Osteoarthritis Cartilage ; 27(12): 1831-1840, 2019 12.

Article em En | MEDLINE | ID: mdl-31536814

Assuntos

Cartilagem Articular/fisiologia; Diferenciação Celular/fisiologia; Condrogênese/fisiologia; Células-Tronco Multipotentes/metabolismo; Osteoartrite do Joelho; Regeneração/fisiologia; 5'-Nucleotidase/metabolismo; Idoso; Idoso de 80 Anos ou mais; Estudos de Casos e Controles; Moléculas de Adesão Celular/metabolismo; Feminino; Citometria de Fluxo; Proteínas Ligadas por GPI/metabolismo; Humanos; Imuno-Histoquímica; Imunofenotipagem; Antígenos Comuns de Leucócito/metabolismo; Masculino; Pessoa de Meia-Idade; Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo; Receptores de Quimiocinas/metabolismo; Receptores de Fatores de Crescimento/metabolismo; Membrana Sinovial/citologia; Antígenos Thy-1/metabolismo

Palavras-chave

Chondrogenesis; MSC isolation; MSC subpopulations; Mesenchymal stem/progenitor cells; Osteoarthritis; Primary MSC; Synovium

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regeneração / Cartilagem Articular / Diferenciação Celular / Osteoartrite do Joelho / Condrogênese / Células-Tronco Multipotentes Tipo de estudo: Observational_studies / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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