Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6.

Toroney, Rebecca; Nielsen, Klaus H; Staley, Jonathan P

Toroney, Rebecca; Nielsen, Klaus H; Staley, Jonathan P.

Afiliação

Toroney R; Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637, USA.
Nielsen KH; Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637, USA.
Staley JP; Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637, USA.

Genes Dev ; 33(21-22): 1555-1574, 2019 11 01.

Article em En | MEDLINE | ID: mdl-31558568

Assuntos

Adenosina Trifosfatases/metabolismo; RNA Helicases DEAD-box/metabolismo; Splicing de RNA/fisiologia; RNA Nuclear Pequeno/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Spliceossomos/metabolismo; Íntrons/genética; Ligação Proteica; Splicing de RNA/genética

Palavras-chave

ATPase; DEAH box; Prp43p; U6 snRNA; disassembly; fidelity; helicase; intron; pre-mRNA splicing; spliceosome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Nuclear Pequeno / Splicing de RNA / Spliceossomos / Adenosina Trifosfatases / Proteínas de Saccharomyces cerevisiae / RNA Helicases DEAD-box Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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